First Author Publications

JA Gilbert, LJ Adhikari, RV Lloyd, TR Halfdanarson, MH Muders, and MM Ames. Molecular Markers for Novel Therapeutic Strategies in Pancreatic Endocrine Tumors. Pancreas 42: 411-421, 2013.
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Supplemental Table 1 | Supplemental Table 2

JA Gilbert and LJ Adhikari, RV Lloyd, J Rubin, P Haluska, JM Carboni, MM Gottardis, and MM Ames. Molecular Markers for Novel Therapies in Neuroendocrine (Carcinoid) Tumors. Endocrine-Related Cancer 17: 623-636, 2010.
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Supplemental Table 1 | Supplemental Table 2 | Supplemental Table 3

JA Gilbert and MP Goetz, CA Reynolds, JN Ingle, KF Giordano, VJ Suman, HE Blair, RB Jenkins, WL Lingle, MM Reinholz, AA Adjei, and MM Ames. Molecular Analysis of Metaplastic Breast Carcinoma: High EGFR Copy Number via Aneusomy. Molecular Cancer Therapeutics 7: 944-951, 2008.
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JA Gilbert, OE Salavaggione, Y Ji, LL Pelleymounter, BW Eckloff, ED Wieben, MM Ames, and RM Weinshilboum. Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics. Clinical Cancer Research 12: 1794-1803, 2006.
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Supplemental Data

JA Gilbert, RV Lloyd, and MM Ames. Lack of Mutations in EGFR in Gastroenteropancreatic Neuroendocrine Tumors. New England Journal of Medicine 353: 209-210, 2005.
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JA Gilbert and LM Frederick, LJ Pobst, and MM Ames. Hydrogen Peroxide Degradation and Selective Carbidopa-Induced Cytotoxicity Against Human Tumor Lines. Biochemical Pharmacology 69: 1159-1166, 2005.
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JA Gilbert, LM Frederick, and MM Ames. The Aromatic-L-Amino Acid Decarboxylase Inhibitor Carbidopa is Selectively Cytotoxic to Human Pulmonary Carcinoid and Small Cell Lung Carcinoma Cells. Clinical Cancer Research 6: 4365-4372, 2000.
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JA Gilbert, LA Bates, and MM Ames. Elevated Aromatic-L-Amino Acid Decarboxylase in Human Carcinoid Tumors. Biochemical Pharmacology 50: 845-850, 1995.
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JA Gilbert, DJ McCormick, MA Pfenning, KS Kanba, LJ Enloe, A Moore, and E Richelson. Neurotensin (8-13): Comparison of Novel Analogs for Stimulation of Cyclic GMP Formation in Neuroblastoma Clone N1E-115 and Receptor Binding to Human Brain and Intact N1E-115 Cells. Biochemical Pharmacology 38: 3377-3382, 1989.
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JA Gilbert, TR Strobel, and E Richelson. Desensitization of Neurotensin Receptor-Mediated Cyclic GMP Formation in Neuroblastoma Clone N1E-115. Biochemical Pharmacology 37: 2833-2838, 1988.
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JA Gilbert, PD Hanson, DJ McCormick, and E Richelson. Rapid Degradation of Neurotensin by Intact Murine Neuroblastoma Cells (Clone N1E-115). Journal of Neurochemistry 49: 1845-1852, 1987.
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JA Gilbert and E Richelson. LANT-6, Xenopsin, and Neuromedin N Stimulate Cyclic GMP at Neurotensin Receptors. European Journal of Pharmacology 129: 379-383, 1986.
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JA Gilbert, CJ Moses, MA Pfenning, and E Richelson. Neurotensin and its Analogs--Correlation of Specific Binding with Stimulation of Cyclic GMP Formation in Neuroblastoma Clone N1E-115. Biochemical Pharmacology 35: 391-397, 1986.
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JA Gilbert and E Richelson. Influence of Delta-Opioid Receptors on Production of Labeled Methionine5-Enkephalin in Murine Neuroblastoma Cells. Journal of Neurochemistry 44: 922-928, 1985.
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JA Gilbert, MA Pfenning, and E Richelson. The Effect of Angiotensins I, II, and III on Formation of Cyclic GMP in Murine Neuroblastoma Clone N1E-115. Biochemical Pharmacology 33: 2527-2530, 1984.
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JA Gilbert and E Richelson. Neurotensin Stimulates Formation of Cyclic GMP in Murine Neuroblastoma Clone N1E-115. European Journal of Pharmacology 99: 245-246, 1984.
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JA Gilbert, EL Knodel, SD Stenstrom, and E Richelson. Function and Regulation of Methionine5-Enkephalin and Its Receptors in Murine Neuroblastoma Cells. Journal of Biological Chemistry 257: 1274-1281, 1982.
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Co-Authored Publications

RA Leon-Ferre, M-Y Polley, H Liu, JA Gilbert, V Cafourek, DW Hillman, A Elkhanany, M Akinhanmi, J Lilyquist, A Thomas, V Negron, JC Boughey, MC Liu, JN Ingle, KR Kalari, FJ Couch, DW Visscher, and MP Goetz. Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer. Breast Cancer Research and Treatment, http://dx.doi.org/10.1007/s10549-017-4499-7, 2017.

SL Safgren, VJ Suman, ML Kosel, JA Gilbert, SA Buhrow, JL Black, DW Northfelt, AS Modak, D Rosen, JN Ingle, MM Ames, JM Reid, and MP Goetz. Evaluation of CYP2D6 Enzyme Activity Using a 13C-Dextromethorphan Breath Test in Women Receiving Adjuvant Tamoxifen. Pharmacogenetics and Genomics 25: 157-163, 2015.

JM Reid, SA Buhrow, JA Gilbert, L Jia, M Shoji, JP Snyder, and MM Ames. Mouse Pharmacokinetics and Metabolism of the Curcumin Analog, 4-Piperidinone,3,5-bis[(2-fluorophenyl)methylene]-acetate(3E,5E) (EF-24; NSC 716993). Cancer Chemotherapy and Pharmacology 73: 1137-1146, 2014.

MS Banck, R Kanwar, AA Kulkarni, GK Boora, F Metge, BR Kipp, L Zhang, EC Thorland, KT Minn, R Tentu, BW Eckloff, ED Wieben, Y Wu, JM Cunningham, DM Nagorney, JA Gilbert, MM Ames, and AS Beutler. The Genomic Landscape of Small Intestine Neuroendocrine Tumors. Journal of Clinical Investigation 123: 2502-2508, 2013.

D Rudin, L Li, N Niu, KR Kalari, JA Gilbert, MM Ames, and L Wang. Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination. Journal of Drug Metabolism & Toxicology 2: 1-9, 2011.

JH Beumer, JL Eiseman, JA Gilbert, JL Holleran, AE Yellow-Duke, DM Clausen, DZ D'Argenio, MM Ames, PA Hershberger, RA Parise, L Bai, JM Covey, and MJ Egorin. Plasma Pharmacokinetics and Oral Bioavailability of the 3,4,5,6- Tetrahydrouridine (THU) Prodrug, Triacetyl-THU (taTHU), in Mice. Cancer Chemotherapy and Pharmacology 67: 421-430, 2011.

NA Kocabas and P Aksoy, LL Pelleymounter, I Moon, J-S Ryu, JA Gilbert, OE Salavaggione, BW Eckloff, ED Wieben, V Yee, RM Weinshilboum, and MM Ames. Gemcitabine Pharmacogenomics: Deoxycytidine Kinase and Cytidylate Kinase Gene Resequencing and Functional Genomics. Drug Metabolism and Disposition 36: 1951-1959, 2008.

DE Zembower, JA Gilbert, and MM Ames. Enantiospecific Syntheses of alpha-(Fluoromethyl)-tryptophan Analogues: Interactions with Tryptophan Hydroxylase and Aromatic L-Amino Acid Decarboxylase. Journal of Medicinal Chemistry 36: 305-313, 1993.

NRF Al-Rodhan, E Richelson, JA Gilbert, DJ McCormick, KS Kanba, MA Pfenning, A Nelson, EW Larson, and TL Yaksh. Structure-antinociceptive activity of neurotensin and some novel analogues in the periaqueductal gray region of the brainstem. Brain Research 557: 227-235, 1991.

TC Spelsberg, TB Sculley, GM Pikler, JA Gilbert, and GR Pearson. Evidence for Two Classes of Chromatin-Associated Epstein-Barr Virus-Determined Nuclear Antigen. Journal of Virology 43: 555-565, 1982.

First Author Scientific Reviews

JA Gilbert and E Richelson. Function of Delta Opioid Receptors in Cultured Cells. Molecular and Cellular Biochemistry 55: 83-91, 1983.
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Articles

JA Gilbert. Improving duodenoscope safety: a work in progress. The Lancet Gastroenterology & Hepatology, http://dx.doi.org/10.1016/S2468-1253(19)30143-8, 2019.
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JA Gilbert and L Melton. Verily project releases millions of factory-reared mosquitoes. Nature Biotechnology, http://dx.doi.org/10.1038/nbt0918-781a, 2018.
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JA Gilbert. Sepsis care bundles: a work in progress. The Lancet Respiratory Medicine, http://dx.doi.org/10.1016/S2213-2600(18)30362-X, 2018.
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JA Gilbert. Advancing towards precision medicine in ARDS. The Lancet Respiratory Medicine, http://dx.doi.org/10.1016/S2213-2600(18)30156-5, 2018.
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JA Gilbert. Effect of increasing glucocorticoids on asthma exacerbations. The Lancet Respiratory Medicine, http://dx.doi.org/10.1016/S2213-2600(18)30118-8, 2018.
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JA Gilbert. CAR T-cells for relapsed B-cell ALL in adults. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(18)30086-X, 2018.
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JA Gilbert. BGJ398 for FGFR-altered advanced cholangiocarcinoma. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(17)30902-6, 2017.
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JA Gilbert. Seasonal and pandemic influenza: global fatigue versus global preparedness. The Lancet Respiratory Medicine, http://dx.doi.org/10.1016/S2213-2600(17)30466-6, 2017.
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JA Gilbert. Pazopanib for advanced liposarcoma. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(17)30663-0, 2017.
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JA Gilbert. Ready-to-use T cells for infection after stem-cell transplant. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(17)30625-3, 2017.
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JA Gilbert. Savolitinib for MET-driven papillary renal cell carcinoma. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(17)30508-9, 2017.
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JA Gilbert. Potential drug targets in small-bowel adenocarcinoma. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(17)30503-X, 2017.
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JA Gilbert. Alectinib surpasses crizotinib for untreated ALK-positive NSCLC. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(17)30482-5, 2017.
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JA Gilbert. Nosocomial nontuberculous mycobacteria infections associated with heater-cooler devices. The Lancet Respiratory Medicine, http://dx.doi.org/10.1016/S2213-2600(17)30109-1, 2017.
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JA Gilbert. Neuroendocrine tumours emerge from the shadows. The Lancet Diabetes & Endocrinology, http://dx.doi.org/10.1016/S2213-8587(16)30332-1, 2016.
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JA Gilbert. PR1 peptide vaccine in myeloid malignancies. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(16)30552-6, 2016.
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JA Gilbert. Transoral robotic surgery for oropharyngeal cancer. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(16)30285-6, 2016.
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JA Gilbert. Reduced intensity transplantation in follicular lymphoma. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(16)00178-9, 2016.
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JA Gilbert. Overuse of PET to monitor lung or oesophageal cancers. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(16)00140-6, 2016.
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JA Gilbert. Prediction of chemotherapy benefit for colon cancers. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(16)00068-1, 2016.
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JA Gilbert. Reducing treatment-related mortality in childhood cancers. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(16)00031-0, 2016.
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JA Gilbert. Adapted paediatric regimen benefits adults with ALL. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(14)70382-1, 2014.
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JA Gilbert. Lanreotide delays progression of neuroendocrine tumours. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(14)70188-3, 2014.
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JA Gilbert. MEK1/2 inhibition delays progression of uveal melanoma. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(14)70298-0, 2014.
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JA Gilbert. Reducing complications from obstructive sleep apnoea. The Lancet Respiratory Medicine, http://dx.doi.org/10.1016/S2213-2600(14)70110-9, 2014.
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JA Gilbert. DNA test offers new option for colon cancer screening. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(14)70134-2, 2014.
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JA Gilbert. Idelalisib: targeting PI3Kdelta in B-cell malignancies. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(14)70052-X, 2014.
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JA Gilbert. Dasatinib as first-line therapy for CML-CP. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(13)70593-X, 2013.
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JA Gilbert. Acute GVHD prophylaxis — atorvastatin for donor and recipient. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(13)70532-1, 2013.
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JA Gilbert. Vintafolide combination for ovarian cancer. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(13)70505-9, 2013.
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JA Gilbert. Colon cancer screening provides long-term protection. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(13)70433-9, 2013.
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JA Gilbert. Ipilimumab for metastatic uveal melanoma. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(13)70369-3, 2013.
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JA Gilbert. Afatinib monotherapy in EGFR-mutant lung adenocarcinoma. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(13)70346-2, 2013.
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JA Gilbert. Lenalidomide as first-line therapy for elderly CLL patients. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(13)70330-9, 2013.
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JA Gilbert. SALL4, a new target in aggressive liver cancer. The Lancet Oncology, http://dx.doi.org/10.1016/S1470-2045(13)70304-8, 2013.
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JA Gilbert. New hormone stimulates pancreatic beta-cell proliferation. The Lancet Diabetes & Endocrinology, http://dx.doi.org/10.1016/S2213-8587(13)70032-9, 2013.
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JA Gilbert. Ponatinib for resistant Ph chromosome-positive leukaemia. The Lancet Oncology 14(1): e9, 2013; http://dx.doi.org/10.1016/S1470-2045(12)70563-6.
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JA Gilbert. Novel therapeutic target in aggressive paediatric AMKL. The Lancet Oncology 14(1): e6, 2013; http://dx.doi.org/10.1016/S1470-2045(12)70536-3.
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JA Gilbert. Aspirin for PIK3CA-mutated colorectal cancer. The Lancet Oncology 13(12): e522, 2012; http://dx.doi.org/10.1016/S1470-2045(12)70505-3.
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JA Gilbert. Detecting Lynch syndrome in patients with colorectal cancer. The Lancet Oncology 13(12): e521, 2012; http://dx.doi.org/10.1016/S1470-2045(12)70487-4.
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JA Gilbert. Therapeutic drug targets in colorectal cancer. The Lancet Oncology 13(9): e372, 2012; http://dx.doi.org/10.1016/S1470-2045(12)70351-0.
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JA Gilbert. Natural gamma radiation and childhood leukaemia. The Lancet Oncology 13(8): e332, 2012; http://dx.doi.org/10.1016/S1470-2045(12)70326-1.
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JA Gilbert. Potential therapeutic target for triple-negative breast cancer. The Lancet Oncology 13(8): e330, 2012; http://dx.doi.org/10.1016/S1470-2045(12)70298-X.
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JA Gilbert. FDA provides fastest drug approval. The Lancet Oncology 13(7): e287, 2012; http://dx.doi.org/10.1016/S1470-2045(12)70238-3.
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Presentations by JA Gilbert at International Scientific Meetings

Analysis of Markers Predictive for Response in Carcinoid Tumors. One hundredth Annual Meeting of the American Association for Cancer Research, Denver, CO, 2009.

Mutational Analysis of the Epidermal Growth Factor Receptor and Stem Cell Factor Receptor Genes in Metaplastic Breast Carcinoma. Twenty-ninth Annual San Antonio Breast Cancer Symposium, San Antonio, TX, 2006.

Gastrointestinal Neuroendocrine Tumors Lack Epidermal Growth Factor Receptor Mutations Predictive of Gefitinib Response. Ninety-sixth Annual Meeting of the American Association for Cancer Research, Anaheim, CA, 2005.

Gemcitabine Pharmacogenetics: Cytidine Deaminase and Deoxycytidylate Deaminase Genotype-to-Phenotype Studies. Ninety-fifth Annual Meeting of the American Association for Cancer Research, Orlando, FL, 2004.

Cytotoxicity of Carbidopa, an Inhibitor of Aromatic-L-Amino Acid Decarboxylase, to Human Pulmonary Carcinoid and Small Cell Lung Carcinoma Cells. Twentyninth Annual Meeting of the Society for Neuroscience, Miami Beach, FL, 1999.

Increased Levels of Aromatic-L-Amino Acid Decarboxylase Protein and mRNA in Human Carcinoid Tumors. Twenty-sixth Annual Meeting of the Society for Neuroscience, Washington, DC, 1996.

Kinetics of Tryptophan Hydroxylase and Aromatic-L-Amino Acid Decarboxylase in Human Carcinoid Tumors. Twenty-third Annual Meeting of the Society for Neuroscience, Washington, DC, 1993.

Characterization of Tryptophan Hydroxylase and Aromatic-L-Amino Acid Decarboxylase in Carcinoid Tumor Tissue. Eighty-second Annual Meeting of the American Association for Cancer Research, Houston, TX, 1991.

Structure-Activity Studies of Novel Neurotensin(8-13) Analogs. Twentieth Annual Meeting of the American Society for Neurochemistry, Chicago, IL, 1989.

Desensitization of Neurotensin Receptor-Mediated Cyclic GMP Formation in Neuroblastoma Clone N1E-115. Seventeenth Annual Meeting of the Society for Neuroscience, New Orleans, LA, 1987.

Rapid Degradation of Neurotensin by Neuroblastoma Clone N1E-115. Sixteenth Annual Meeting of the Society for Neuroscience, Washington, DC, 1986.

Comparison of Neurotensin Analogs for Specific Binding to Neuroblastoma Clone N1E-115 and Intracellular Stimulation of Cylic GMP. Fifteenth Annual Meeting of the Society for Neuroscience, Dallas, TX, 1985.

Neurotensin Stimulates Cyclic GMP Formation in Neuroblastoma Clone N1E-115 and Rat Cerebellum. Fourteenth Annual Meeting of the Society for Neuroscience, Anaheim, CA, 1984.

Synthesis and Function of Met5-Enkephalin in a Mouse Neuroblastoma Clone. Twelfth Annual Meeting of the American Society for Neurochemistry, Richmond, VA, 1981.

Evidence that Class II EBNA is a Histonelike Protein. International Conference on Human Herpesviruses, Atlanta, GA, 1980.

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